| Issue | #100 |
| Published | August 2006 |
| Cover Price | 4.99 USD |
| Pages | 52 |
| Editing | Rob Levin |
| Characters | Witchblade [Sara Pezzini] |
| Genre | fantasy; crime |
| Pencils | Michael Turner |
| Inks | Marc Silvestri |
| Colors | Stjepan Sejic |
| Letters | Typeset |
| Notes | Cover is a tribute to the cover to issue #1 and depicts Sara sitting down and holding up her flaming Witchblade hand. |
| Characters | Witchblade [Sara Pezzini]; Witchblade [Danielle Baptiste] |
| Genre | fantasy; crime |
| Pencils | Michael Choi |
| Inks | Michael Choi |
| Colors | Sonia Oback |
| Letters | Typeset |
| Notes | Cover depicts Sara sitting down and Danielle standing in the background to the right and looking over her shoulder. |
| Characters | Witchblade [Sara Pezzini] |
| Genre | fantasy; crime |
| Pencils | Marc Silvestri |
| Inks | Joe Weems |
| Colors | John Starr |
| Letters | Typeset |
| Notes | Cover depicts Sara blowing out candles on a birthday cake. |
| Characters | Witchblade [Manga Version] |
| Genre | fantasy; crime |
| Pencils | Gonzo Animation |
| Inks | Gonzo Animation |
| Colors | Gonzo Animation |
| Letters | Typeset |
| Notes | Cover depicts an animated Manga Witchblade licking one of her fingers. |
| Characters | Witchblade [Danielle Baptiste] |
| Genre | fantasy; crime |
| Pencils | Joseph Michael Linsner (Painted) |
| Inks | Joseph Michael Linsner (Painted) |
| Colors | Joseph Michael Linsner (Painted) |
| Letters | Typeset |
| Notes | Cover depicts Danielle as the Witchblade standing against a red background. |
| Characters | Witchblade [Sara Pezzini] |
| Genre | fantasy; crime |
| Pencils | Michael Turner |
| Inks | Michael Turner |
| Letters | Typeset |
| Notes | Variant cover distributed through Fantastic Realms with three versions of the cover, one in color, one in black and white and one in black and white with a blue foil logo; The black and white cover variant was also distributed as a "VIP" variant at the Wizard World Chicago comic con and has a Wizard World Chicago bullet in the lower left corner in addition to the Fantastic Realms bullet in the lower right corner; Cover depicts Sara crouching down and facing right. |
| Characters | Witchblade [Sara Pezzini]; GUEST: Patrick Gleason; VILLAIN: Jake McCarthy (death); CAMEOS: Witchblade [Anne Bonny]; Witchblade [Shiori-Sama]; Witchblade [Queen Kijani]; Witchblade [Unnamed Western Bearer]; Witchblade [Unnamed Musketeer Bearer]; Witchblade [Unnamed Russian Bearer]; Witchblade [Maitea]; Witchblade [Katarina]; Witchblade [Samantha]; Witchblade [Una]; Tora No Shi; Danielle Baptiste |
| Synopsis | Patrick buys flowers to meet Sara at the Empire State Building but drops them in the street when he notices a battle going on at the top; Sara and Patrick battle a powerful demon possessing Jake McCarthy; Sara drives it off momentarily with the Witchblade and Jake shoots and kills himself rather than be controlled by the monster any more; Danielle finds Patrick's dropped flowers and picks them up from the street. |
| Genre | fantasy; crime |
| Script | Ron Marz |
| Pencils | Marc Silvestri (pg. 1); Brian Ching (pg. 2); Christian Gossett (pg. 3); Billy Tan (pg. 4); Keu Cha (pg. 5); Randy Green (pg. 6); Michael Choi (pgs. 7-18); Adriana Melo (pgs. 19-33) |
| Inks | Billy Tan (pg. 4); Joe Weems (pg. 6); Mariah Benes (pgs. 19-25, 27-28, 31-32); Haberlin Studios (pgs. 26, 29); Rick Basaluda (pg. 30) |
| Colors | Sonia Oback (pgs. 1, 7-18, 23-33); Blond (pgs. 3-6, 19-22); Michael Atiyeh (pg. 2) |
| Letters | Troy Peteri |
| Notes | Pages with no inking credits were shot directly from pencils. |
| Genre | fantasy; crime |
| Script | Ron Marz; Renae Geerlings |
| Pencils | Michael Choi |
| Inks | Michael Choi |
| Colors | Sonia Oback |
| Letters | Typeset |
| Notes | Interview with writer Ron Marz. |
| Characters | Witchblade [Samantha]; Witchblade [Una]; Witchblade [Queen Kijani]; Kenneth Irons |
| Genre | fantasy; crime |
| Script | Ron Marz |
| Pencils | Randy Green; Chris Bachalo; Michael Turner |
| Letters | Typeset |
| Notes | Promo for upcoming comic consisting of character profiles of Witchblade characters. |