| Issue | #43 |
| Published | August 2000 |
| Cover Price | $2.25; $3.50 CAD |
| Pages | 36 |
| Editing | Mike Marts; Mike Raicht (assistant) |
| Characters | Deadpool |
| Genre | Superhero; Humor |
| Pencils | James Calafiore (signed) |
| Inks | Peter Palmiotti (signed) |
| Colors | Tom Chu (signed) |
| Characters | Deadpool [Wade Wilson]; Constrictor [Frank Schlichting]; Titania [Mary MacPherran; also as Skeeter]; Corsair [Christopher Summers] (cameo); Absorbing Man [Crusher Creel]; Dirty Wolff; Lucifer Rasputin; Reverend Michael Ibn al-hajj Achebe (cameo) |
| Synopsis | The Merc with a Mouth faces his hardest challenge yet-getting home from outer space! After the events of DEADPOOL #41, Wade Wilson is stranded in space with the alien known as Dirty Wolff! Will Deadpool find his way back to Earth, or will he be destroyed by the deadly interstellar space warden named Rasputin?! |
| Genre | Superhero; Humor |
| Script | James Owsley [as Christopher Priest] |
| Pencils | James Calafiore |
| Inks | Jon Holdredge |
| Colors | Shannon Blanchard |
| Letters | Chris Eliopoulos |
| Letters | typeset |
| Notes | Spotlight on HELLCAT #1 and X-MEN: THE MOVIE. Marvel checklist for comics sold July 5, 2000. |
| Letters | typeset |
| Notes | Letters from readers - Michael McCullough, Casey Aron, Michael Bregman, Robert Acquarulo and Brandon Thomas. Preview of cover to DEADPOOL #44. |