| Issue | #46 |
| Published | April 1977 |
| Cover Price | 0.30 |
| Pages | 36 |
| Editing | Archie Goodwin |
| Notes | Cover signed beside Scorpio's head. |
| Characters | Defenders [Hulk [Bruce Banner]; Hellcat [Patsy Walker]; Nighthawk [Kyle Richmond]; Valkyrie]; Scorpio [Jacob Fury] |
| Genre | superhero |
| Pencils | Ed Hannigan (signed) |
| Inks | Joe Sinnott (signed) |
| Letters | Dan Crespi |
| Notes | Cover signed beside Scorpio's head. |
| Reprinted | In Essential Defenders (Marvel, 2005 series) #3 |
| Characters | Defenders [Hulk [Bruce Banner]; Nighthawk [Kyle Richmond]; Power Man [Luke Cage]; Valkyrie; Red Guardian [Dr. Tanya Belinksy]; Dr. Strange [Stephen Strange]; Hellcat [Patsy Walker]]; Nick Fury; Scorpio [Jacob Fury]; The Elf with a Gun; Jack Norriss; Aragorn; S.H.I.E.L.D. |
| Synopsis | When Dr. Strange, Power Man and Red Guardian all quit the Defenders, Nighthawk and the remaining Defenders move to their country "headquarters", where they discover that Scorpio is there waiting for them. |
| Genre | superhero |
| Script | Roger Slifer; David Kraft |
| Pencils | Keith Giffen (breakdowns); Klaus Janson (finished art) |
| Inks | Klaus Janson |
| Colors | Dave Hunt |
| Letters | Irving Watanabe [as Irv Watanabe] |
| Notes | Doctor Strange, Power Man, & Red Guardian leave the Defenders; the Elf gets hit by a Mac-Ray Moving Co. truck. |
| Reprinted | In Essential Defenders (Marvel, 2005 series) #3 |
| Letters | typeset |
| Notes | Letters from Ralph Gardner, Dave Stiles, Hoy R. Murphy Jr., Tom Brown, Larry Lisowski and Bryan Sowder. This sequence appears between pages 11 and 12 od the previous sequence. |
| Characters | Spider-Man; Aldo Moomjay; The Foe |
| Synopsis | Spider-Man stops a crooked boxing match. |
| Genre | superhero |
| Pencils | Ross Andru |
| Inks | Mike Esposito |
| Letters | Irving Watanabe |
| Notes | This sequence appears between pages 15 and 16 of the first sequence. Hostess Cupcake ad. |