| Issue | #280 |
| Published | June 1950 |
| Cover Price | 0.10 USD |
| Pages | 52 |
| Editing | ? |
| Notes | Indicia title is "Walter Lantz ANDY PANDA in THE ISLE OF MECHANICAL MEN, No. 280. Code number is A.P.O.S. #280-506. Copyright 1950 by Walter Lantz Productions, Inc. |
| Characters | Andy Panda; Hiram (robot); Charlie Chicken |
| Synopsis | Hiram the robot leading Charlie on a leash and collar. |
| Genre | funny animals |
| Pencils | Dan Gormley |
| Inks | Dan Gormley |
| Notes | Pencils and inks credits for this sequence from Alberto Becattini (May 14, 2007) |
| Characters | Andy Panda |
| Synopsis | First line: "Cough! Cough!" |
| Genre | funny animals |
| Pencils | Dick Hall |
| Notes | Inside front cover; black and white; Pencils credit for this sequence from Alberto Becattini (May 14, 2007) |
| Characters | Andy Panda; Charlie Chicken; Hiram (robot); Professor; Rocky |
| Synopsis | A tornado snatches Andy and Charlie while they are fishing and deposits them on a strange island. The island is the hideout of an old professor and his helper Rocky. The professor is in the process of creating a robot army to conquer the world. With the assistance of Hiram, a rebel robot, Andy and Charlie cause the robot army to destroy itself. |
| Genre | funny animals; science fiction |
| Pencils | Dan Gormley |
| Notes | Pencils credit for this sequence from Alberto Becattini (May 14, 2007). |
| Characters | Andy Panda; Charlie Chicken; Doc Walrus; Doc Woodpecker |
| Synopsis | Charlie comes down with a case of sleeping sickness and Andy has to take him to Africa so he can be bitten by a Tsetse Fly as a cure. (The first bite causes the sickness and the second one is an antidote, according to this story.) In Africa they meet Doc Woodpecker, who provides the cure. |
| Genre | funny animals; adventure |
| Pencils | Dan Gormley |
| Inks | Suzanne Seaborne |
| Notes | Doc Woodpecker is identical in appearance to Woody Woodpecker, but the characters interact like they've never met before. Pencils and inks credits for this sequence from Alberto Becattini (May 14, 2007). |
| Characters | Andy Panda |
| Synopsis | First line: "730-731-732-733-734-" |
| Genre | funny animals |
| Pencils | Dick Hall |
| Inks | Suzanne Seaborne |
| Notes | Inside back cover; black and white. Pencils and inks credits for this sequence from Alberto Becattini (May 14, 2007). |
| Characters | Andy Panda |
| Synopsis | First line: "Gee whiz! I wish people would stop bothering me!" |
| Genre | funny animals |
| Pencils | Dick Hall |
| Inks | Suzanne Seaborne |
| Notes | Back cover. Pencils and inks credits for this sequence from Alberto Becattini (May 14, 2007). |