| Issue | #22 |
| Published | September 1943 |
| Frequency | Monthly |
| Cover Price | 0.10 USD |
| Pages | 68 |
| Editing | George Brenner |
| Notes | Copyright 1943 by Comic Magazines. |
| Characters | Plastic Man [Eel O'Brian]; Spirit [Denny Colt] |
| Genre | Superhero |
| Pencils | Jack Cole |
| Inks | Jack Cole |
| Reprinted | in Plastic Man Archives (DC, 1998 series) #2 (December 2000) |
| Characters | Plastic Man [Eel O'Brian]; Woozy Winks; Chief Branner (first use of name); Bright Eyes (first appearance); VILLAINS: The Sphinx (first appearance; dies); Mr. Grimley (first appearance; flashback); Mrs. Grimley (first appearance; flashback) |
| Synopsis | Plas rescues a young orphan from the Sphinx. |
| Genre | Superhero |
| Script | Jack Cole |
| Pencils | Jack Cole |
| Inks | Jack Cole |
| Letters | Jack Cole |
| Reprinted | in Jack Cole and Plastic Man Forms Stretched to Their Limits (Chronicle Books, 2001 series) #nn; in Plastic Man Archives (DC, 1998 series) #2 (December 2000) |
| Genre | gag |
| Script | Joe Devlin |
| Pencils | Joe Devlin |
| Inks | Joe Devlin |
| Characters | Spirit [Denny Colt] |
| Genre | Superhero |
| Script | Will Eisner |
| Pencils | Will Eisner |
| Inks | Will Eisner |
| Colors | Joe Kubert |
| Letters | Sam Rosen |
| Reprinted | from Spirit, The (Register and Tribune Syndicate, 1940 series) #8/18/1940 |
| Characters | Human Bomb [Roy Lincoln]; The Bombardiers [Montague T. McGurk; Swordo; Red Rogers] (last appearance) |
| Genre | superhero |
| Script | Paul Gustavson |
| Pencils | Paul Gustavson |
| Inks | Paul Gustavson |
| Characters | Manhunter [Dan Richards] |
| Genre | superhero |
| Pencils | John Cassone |
| Inks | John Cassone |
| Characters | Burp the Twerp |
| Genre | gag |
| Script | Jack Cole |
| Pencils | Jack Cole |
| Inks | Jack Cole |
| Letters | Jack Cole |
| Characters | Destiny |
| Genre | detective; superhero |
| Pencils | Jack Keller? |
| Inks | Jack Keller? |
| Characters | Dick Mace |
| Genre | Detective |
| Script | Robert Hyatt ? |
| Letters | typeset |
| Characters | Phantom Lady [Sandra Knight]; The Raven; Spider Widow |
| Genre | superhero |
| Pencils | Arthur Peddy? |
| Inks | Arthur Peddy? |
| Genre | humor |
| Script | Gill Fox |
| Pencils | Gill Fox |
| Inks | Gill Fox |
| Letters | Gill Fox ? |
| Characters | Flatfoot Burns |
| Genre | humor; detective |
| Script | Al Stahl |
| Pencils | Al Stahl |
| Inks | Al Stahl |