| Issue | #25 |
| Published | December 2006 |
| Cover Price | $2.99 |
| Pages | 36 |
| Editing | Tom Brevoort (Consulting); Aubrey Sitterson |
| Notes | Last Issue; Cover is a tribute to the Scott Kolins cover of issue #1. |
| Characters | Silver Surfer; Storm; Moon Knight; Spider-Man; Dr. Strange; Sentry; Mr. Fantastic; Invisible Woman; Human Torch; Thing; Nightcrawler; Iron Fist; Black Cat; Black Panther; Cyclops; Captain America; Iron Man; Wolverine; X-23; Black Widow; She-Hulk; Lockjaw; Punisher; Cable; Man-Thing; Wasp; Ant-Man |
| Genre | superhero |
| Pencils | Phil Hester |
| Inks | Ande Parks |
| Colors | Edgar Delgado |
| Letters | Typeset |
| Notes | Last Issue; Cover is a tribute to the Scott Kolins cover of issue #1. |
| Characters | FEATURE: Dr. Strange; Spider-Man; Captain America; Ms. Marvel; Luke Cage [Power Man]; She-Hulk; Wolverine; Crusader; GUESTS: Mary Jane; Reed Richards 2099; Speedball; Sleepwalker; Darkhawk; Terror; X-23; Gravity; Mutant 2099; Dagger; VILLAIN: Titannus; CAMEOS: John Jameson; Wong |
| Synopsis | Dr. Strange gathers our heroes for one last time to face down a mindless Titannus who is being controlled by power-mad Japanese computer scientists. |
| Genre | superhero |
| Script | Robert Kirkman |
| Pencils | Andy Kuhn |
| Inks | Andy Kuhn |
| Colors | Studio F's Marte Gracia |
| Letters | Virtual Calligraphy's Rus Wooton |